HMM Summary Page: TIGR00727

Functionsmall oligopeptide transporter, OPT family
Trusted Cutoff438.70
Domain Trusted Cutoff438.70
Noise Cutoff299.45
Domain Noise Cutoff299.45
Isology Typeequivalog
HMM Length681
Mainrole CategoryTransport and binding proteins
Subrole CategoryAmino acids, peptides and amines
Gene Ontology TermGO:0015198: oligopeptide transporter activity molecular_function
AuthorHaft DH
Entry DateFeb 22 2000 11:31AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents a family of transporters of small oligopeptides, demonstrated experimentally in three different species of yeast. A set of related proteins from the plant Arabidopsis thaliana forms an outgroup to the yeast set by neighbor joining analysis but is remarkably well conserved and is predicted here to have equivalent function.
ReferencesA2 hmmalign RN [1] RM 97195785 RT An oligopeptide transport gene from Candida albicans. RA Lubkowitz MA, Hauser L, Breslav M, Naider F, Becker JM RL Microbiology 1997 Feb;143 ( Pt 2):387-96 RN [2] RM 98305694 RT Schizosaccharomyces pombe isp4 encodes a transporter representing a novel family of oligopeptide transporters. RA Lubkowitz MA, Barnes D, Breslav M, Burchfield A, Naider F, Becker JM RL Mol Microbiol 1998 May;28(4):729-41 DR EXPERIMENTAL; EGAD|151451|161614; Candida albicans DR EXPERIMENTAL; EGAD|87330|95040; Schizosaccharomyces pombe DR EXPERIMENTAL; EGAD|56682|YPR194C; Saccharomyces cerevisiae