HMM Summary Page: TIGR00719

FunctionL-serine dehydratase, iron-sulfur-dependent, beta subunit
Gene SymbolsdaAB
Trusted Cutoff161.20
Domain Trusted Cutoff161.20
Noise Cutoff45.80
Domain Noise Cutoff45.80
Isology Typeequivalog
EC Number4.3.1.17
HMM Length208
Mainrole CategoryEnergy metabolism
Subrole CategoryAmino acids and amines
Gene Ontology TermGO:0003941: L-serine ammonia-lyase activity molecular_function
GO:0006094: gluconeogenesis biological_process
GO:0006565: L-serine catabolic process biological_process
AuthorHaft DH
Entry DateFeb 1 2000 10:52AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis enzyme is also called serine deaminase. This model describes the beta chain of an iron-sulfur-dependent L-serine dehydratase, as in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of beta chains from the homologous region of single chain forms such as found in E. coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases.
ReferencesA2 hmmalign AL clustalw RM 97386436