HMM Summary Page: TIGR00716

Functionribonuclease HIII
Gene SymbolrnhC
Trusted Cutoff161.20
Domain Trusted Cutoff161.20
Noise Cutoff80.20
Domain Noise Cutoff80.20
Isology Typeequivalog
EC Number3.1.26.4
HMM Length284
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0004523: ribonuclease H activity molecular_function
GO:0005737: cytoplasm cellular_component
GO:0006401: RNA catabolic process biological_process
AuthorHaft DH
Entry DateFeb 1 2000 10:52AM
Last ModifiedDec 19 2011 1:20PM
CommentThis enzyme cleaves RNA from DNA-RNA hybrids. Two types of ribonuclease H in Bacillus subtilis, RNase HII (rnhB) and RNase HIII (rnhC), are both known experimentally and are quite similar to each other. The only RNase H homolog in the Mycoplasmas resembles rnhC. Archaeal forms resemble HII more closely than HIII. This model describes bacterial RNase III.
ReferencesAL msa_ncbi DR EXPERIMENTAL; EGAD|107727|BS2856; Bacillus subtilis DR HAMAP; MF_00053; 65 of 67