HMM Summary Page: TIGR00704

FunctionNa/Pi-cotransporter II-related protein
Trusted Cutoff210.10
Domain Trusted Cutoff210.10
Noise Cutoff100.30
Domain Noise Cutoff100.30
Isology Typehypoth_equivalog
HMM Length308
Mainrole CategoryTransport and binding proteins
Subrole CategoryCations and iron carrying compounds
AuthorHaft DH
Entry DateFeb 1 2000 10:52AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes essentially the full length of an uncharacterized protein from Bacillus subtilis and correponding lengths of longer proteins from E. coli and Treponema pallidum. PSI-BLAST analysis converges to demonstrate homology to one other group of proteins, type II sodium/phosphate (Na/Pi) cotransporters. A well-conserved repeated domain in this family, approximately 60 residues in length, is also repeated in the Na/Pi cotransporters, although with greater spacing between the repeats. The two families share additional homology in the region after the first repeat, share the properly of having extensive hydrophobic regions, and may be similar in function.
ReferencesDR InterPro; IPR003841 DR PFAM; PF02690