HMM Summary Page: TIGR00699

Function4-aminobutyrate aminotransferase
Trusted Cutoff567.15
Domain Trusted Cutoff567.15
Noise Cutoff251.20
Domain Noise Cutoff251.20
Isology Typeequivalog
EC Number2.6.1.19
HMM Length464
Mainrole CategoryCentral intermediary metabolism
Subrole CategoryOther
Gene Ontology TermGO:0003867: 4-aminobutyrate transaminase activity molecular_function
GO:0008152: metabolic process biological_process
AuthorHaft DH
Entry DateFeb 1 2000 10:52AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis enzyme is a class III pyridoxal-phosphate-dependent aminotransferase. This model describes known eukaryotic examples of the enzyme. The degree of sequence difference between this set and known bacterial examples is greater than the distance between either set the most similar enzyme with distinct function, and so separate models are built for prokaryotic and eukaryotic sets. Alternate names include GABA transaminase, gamma-amino-N-butyrate transaminase, and beta-alanine--oxoglutarate aminotransferase.
ReferencesA2 hmmalign AL clustalw DR PROSITE; PDOC00519; Aminotransferases class-III pyridoxal-phosphate attachment site DR PFAM; PF00202; Aminotransferases class-III pyridoxal-phosphate
Genome PropertyGenProp0233: GABA utilization (HMM)