| Accession | TIGR00696 |
| Name | wecG_tagA_cpsF |
| Function | glycosyltransferase, WecB/TagA/CpsF family |
| Trusted Cutoff | 69.00 |
| Domain Trusted Cutoff | 69.00 |
| Noise Cutoff | 37.80 |
| Domain Noise Cutoff | 37.80 |
| Isology Type | superfamily |
| EC Number | 2.4.1.- |
| HMM Length | 178 |
| Mainrole Category | Cell envelope |
| Subrole Category | Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
| Gene Ontology Term | GO:0016757: transferase activity, transferring glycosyl groups molecular_function |
| | GO:0043163: cell envelope organization biological_process |
| Author | Haft DH, Loftus BJ |
| Entry Date | Jan 13 2000 2:41PM |
| Last Modified | Nov 15 2011 9:42AM |
| Comment | The WecG member of this superfamily, believed to be UDP-N-acetyl-D-mannosaminuronic acid transferase, plays a role in enterobacterial common antigen (eca) synthesis in Escherichia coli. Another family member, the Bacillus subtilis TagA protein, is involved in the biosynthesis of the cell wall polymer poly(glycerol phosphate). The third family member, CpsF, CMP-N-acetylneuraminic acid synthetase has a role in the capsular polysaccharide biosynthesis pathway. |
| References | DR ECOCYC; EG11458; wecG
RM 96228704
RT Characterization of cpsF and its product CMP-N-acetylneuraminic acid synthetase, a group B streptococcal enzyme that can function in K1 capsular polysaccharide biosynthesis in Escherichia coli.
RA Haft RF, Wessels MR, Mebane MF, Conaty N, Rubens CE
RL Mol Microbiol 1996 Feb;19(3):555-63
DR HAMAP; MF_01001; 32 of 33 |
| Genome Property | GenProp0973: Enterobacterial common antigen (ECA) (HMM-CLUST) |
