| Accession | TIGR00693 |
| Name | thiE |
| Function | thiamine-phosphate diphosphorylase |
| Gene Symbol | thiE |
| Trusted Cutoff | 145.10 |
| Domain Trusted Cutoff | 145.10 |
| Noise Cutoff | 60.35 |
| Domain Noise Cutoff | 60.35 |
| Isology Type | equivalog_domain |
| EC Number | 2.5.1.3 |
| HMM Length | 197 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Thiamine |
| Gene Ontology Term | GO:0004789: thiamine-phosphate diphosphorylase activity molecular_function |
| | GO:0009228: thiamine biosynthetic process biological_process |
| Author | Loftus BJ, Haft DH |
| Entry Date | Jan 13 2000 2:41PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model represents the thiamine-phosphate pyrophosphorylase, ThiE, of a number of bacteria, and N-terminal domains of bifunctional thiamine proteins of Saccharomyces cerevisiae and Schizosaccharomyces pombe, in which the C-terminal domain corresponds to the bacterial hydroxyethylthiazole kinase (EC 2.7.1.50), ThiM.
This model includes ThiE from Bacillus subtilis but excludes its paralog, the regulatory protein TenI (SP:P25053), and neighbors of TenI. |
| References | DR SWISSPROT; P30137
DR ECOCYC; EG11586; thiE
RM 98363648
DR EXPERIMENTAL; GP|2746079|gb|AAC31298.1||AF015310; Brassica napus
DR EXPERIMENTAL; EGAD|56426|YPL214C; Saccharomyces cerevisiae
DR EXPERIMENTAL; EGAD|10927|EC3993; Escherichia coli
DR HAMAP; MF_01327; 11 of 11 |
| Genome Property | GenProp0254: thiamine: TPP from HMP-PP and HET-P (HMM) |
