HMM Summary Page: TIGR00668

Functionbis(5'-nucleosyl)-tetraphosphatase (symmetrical)
Gene SymbolapaH
Trusted Cutoff222.85
Domain Trusted Cutoff222.85
Noise Cutoff169.65
Domain Noise Cutoff169.65
Isology Typeequivalog
EC Number3.6.1.41
HMM Length279
Mainrole CategoryCellular processes
Subrole CategoryAdaptations to atypical conditions
Gene Ontology TermGO:0006139: nucleobase-containing compound metabolic process biological_process
GO:0008803: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity molecular_function
AuthorLoftus BJ, Haft DH
Entry DateJan 13 2000 2:40PM
Last ModifiedFeb 14 2011 3:27PM
CommentDiadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase.
ReferencesGA hmmsearch AL clustalw DR SWISSPROT; P05637 DR ECOCYC; EG10048; apaH DR HAMAP; MF_00199; 135 of 137