HMM Summary Page: TIGR00649

Functionbeta-CASP ribonuclease, RNase J family
Trusted Cutoff400.00
Domain Trusted Cutoff400.00
Noise Cutoff250.00
Domain Noise Cutoff250.00
Isology Typesubfamily
EC Number3.1.-.-
HMM Length546
Mainrole CategoryHypothetical proteins
Subrole CategoryConserved
AuthorLoftus BJ, Haft DH
Entry DateNov 3 1999 10:19AM
Last ModifiedSep 13 2014 4:12PM
CommentThis family of metalloenzymes includes RNase J1 and RNase J2, involved in mRNA degradation in a wide range of organism.
ReferencesRN [1] RM PMID:15831787 RT Ribonucleases J1 and J2: two novel endoribonucleases in B.subtilis with functional homology to E.coli RNase E. RA Even S, Pellegrini O, Zig L, Labas V, Vinh J, Brechemmier-Baey D, Putzer H RL Nucleic Acids Res. 2005 Apr 14;33(7):2141-52. RN [2] RM PMID:23403287 RT Emergence of the beta-CASP ribonucleases: highly conserved and ubiquitous metallo-enzymes involved in messenger RNA maturation and degradation. RA Dominski Z, Carpousis AJ, Clouet-d'Orval B RL Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):532-51.