HMM Summary Page: TIGR00647

FunctionDNA-binding protein WhiA
Gene SymbolwhiA
Trusted Cutoff44.10
Domain Trusted Cutoff44.10
Noise Cutoff38.25
Domain Noise Cutoff38.25
Isology Typeequivalog
HMM Length304
Mainrole CategoryHypothetical proteins
Subrole CategoryConserved
AuthorLoftus BJ, Haft DH
Entry DateNov 3 1999 10:19AM
Last ModifiedMay 27 2014 6:33PM
CommentThis family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation.
ReferencesRN [1] RM PMID:24097947 RT The conserved DNA-binding protein WhiA is involved in cell division in Bacillus subtilis. RA Surdova K, Gamba P, Claessen D, Siersma T, Jonker MJ, Errington J, Hamoen LW RL J Bacteriol. 2013 Dec;195(24):5450-60. doi: 10.1128/JB.00507-13. RN [2] RM PMID:10986251 RT WhiA, a protein of unknown function conserved among gram-positive bacteria, is essential for sporulation in Streptomyces coelicolor A3(2). RA Ainsa JA, Ryding NJ, Hartley N, Findlay KC, Bruton CJ, Chater KF RL J Bacteriol. 2000 Oct;182(19):5470-8.