HMM Summary Page: TIGR00645

FunctionTIGR00645 family protein
Trusted Cutoff144.40
Domain Trusted Cutoff144.40
Noise Cutoff34.85
Domain Noise Cutoff34.85
Isology Typehypoth_equivalog
HMM Length167
Mainrole CategoryHypothetical proteins
Subrole CategoryConserved
AuthorHaft DH
Entry DateNov 3 1999 10:19AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis conserved hypothetical protein with four predicted transmembrane regions is found in E. coli, Haemophilus influenzae, and Helicobacter pylori, among completed genomes. A similar protein from Aquifex aeolicus appears to share a central region of homology and a similar overall arrangement of hydrophobic stretches, and forms a bidirectional best hit with several members of the seed alignment. However, it is uncertain whether the observed similarity represents full-length homology and/or equivalent function, and so it is excluded from the seed and scores below the trusted cutoff.
ReferencesDR HAMAP; MF_00143; 61 of 62