HMM Summary Page: TIGR00633

Functionexodeoxyribonuclease III (xth)
Trusted Cutoff99.05
Domain Trusted Cutoff99.05
Noise Cutoff82.15
Domain Noise Cutoff82.15
Isology Typesubfamily
EC Number3.1.11.2
HMM Length255
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
AuthorLoftus BJ, Eisen JA
Entry DateOct 20 1999 11:57AM
Last ModifiedFeb 14 2011 3:27PM
CommentAll proteins in this family for which functions are known are 5' AP endonucleases that funciton in base excision repair and the repair of abasic sites in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
ReferencesA2 hmmalign GA hmmsearch DR EGAD; 27876; DR SWISSPROT; P44318; RM 92051291;