HMM Summary Page: TIGR00632

FunctionDNA mismatch endonuclease Vsr
Gene Symbolvsr
Trusted Cutoff97.85
Domain Trusted Cutoff97.85
Noise Cutoff44.85
Domain Noise Cutoff44.85
Isology Typesubfamily
EC Number3.1.-.-
HMM Length119
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0004520: endodeoxyribonuclease activity molecular_function
GO:0006298: mismatch repair biological_process
AuthorLoftus BJ, Eisen JA, Haft DH
Entry DateOct 20 1999 11:57AM
Last ModifiedFeb 14 2011 3:27PM
CommentAll proteins in this family for which functions are known are G:T mismatch endonucleases that function in a specialized mismatch repair process used usually to repair G:T mismatches in specific sections of the genome. This family was based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). Members of this family typically are found near to a DNA cytosine methyltransferase.
ReferencesDR SWISSPROT; P09184; RN [1] RM PMID:2198248 RT A gene required for very short patch repair in Escherichia coli is adjacent to the DNA cytosine methylase gene. RA Sohail A, Lieb M, Dar M, Bhagwat AS RL J Bacteriol. 1990 Aug;172(8):4214-21.
Genome PropertyGenProp0767: very short patch repair (HMM)