HMM Summary Page: TIGR00631

Functionexcinuclease ABC subunit B
Gene SymboluvrB
Trusted Cutoff750.10
Domain Trusted Cutoff750.10
Noise Cutoff402.55
Domain Noise Cutoff402.55
Isology Typeequivalog
EC Number3.1.25.-
HMM Length658
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0006289: nucleotide-excision repair biological_process
GO:0009380: excinuclease repair complex cellular_component
GO:0009381: excinuclease ABC activity molecular_function
AuthorLoftus BJ, Eisen JA
Entry DateOct 20 1999 11:57AM
Last ModifiedFeb 14 2011 3:27PM
CommentAll proteins in this family for wich functions are known are DNA helicases that function in the nucleotide excision repair and are endonucleases that make the 3' incision next to DNA damage. They are part of a pathway requiring UvrA, UvrB, UvrC, and UvrD homologs. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University)
ReferencesGA hmmsearch GA hmmsearch GA hmmsearch RM 86176773; DR HAMAP; MF_00204; 281 of 283
Genome PropertyGenProp0114: nucleotide excision repair (HMM)
GenProp0799: bacterial core gene set, exactly 1 per genome (HMM)