Accession | TIGR00630 |
Name | uvra |
Function | excinuclease ABC subunit A |
Gene Symbol | uvrA |
Trusted Cutoff | 729.80 |
Domain Trusted Cutoff | 729.80 |
Noise Cutoff | 289.80 |
Domain Noise Cutoff | 289.80 |
Isology Type | equivalog |
EC Number | 3.1.25.- |
HMM Length | 924 |
Mainrole Category | DNA metabolism |
Subrole Category | DNA replication, recombination, and repair |
Gene Ontology Term | GO:0006289: nucleotide-excision repair biological_process |
| GO:0009380: excinuclease repair complex cellular_component |
| GO:0009381: excinuclease ABC activity molecular_function |
Author | Loftus BJ, Eisen JA |
Entry Date | Oct 20 1999 11:57AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair.
This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). |
References | GA hmmsearch
DR EGAD; 6128;
DR HAMAP; MF_00205; 90 of 94 |
Genome Property | GenProp0114: nucleotide excision repair (HMM) |