| Accession | TIGR00619 |
| Name | sbcd |
| Function | exonuclease SbcCD, D subunit |
| Gene Symbol | sbcD |
| Trusted Cutoff | 77.65 |
| Domain Trusted Cutoff | 77.65 |
| Noise Cutoff | 67.25 |
| Domain Noise Cutoff | 67.25 |
| Isology Type | subfamily |
| HMM Length | 252 |
| Mainrole Category | DNA metabolism |
| Subrole Category | DNA replication, recombination, and repair |
| Gene Ontology Term | GO:0004527: exonuclease activity molecular_function |
| | GO:0006260: DNA replication biological_process |
| | GO:0006310: DNA recombination biological_process |
| Author | Loftus BJ, Eisen JA |
| Entry Date | Oct 20 1999 11:56AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | All proteins in this family for which functions are known are double-stranded DNA exonuclease (as part of a complex with SbcC homologs). This complex functions in the initiation of recombination and recombinational repair and is particularly important in regulating the stability of DNA sections that can form secondary structures.
This family is likely homologous to the MRE11 family.
This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). |
| References | A2 hmmalign
GA hmmsearch
DR EGAD; 9310;
DR SWISSPROT; P13457;
RM 90045931; |
