HMM Summary Page: TIGR00618

Functionexonuclease SbcC
Trusted Cutoff478.50
Domain Trusted Cutoff478.50
Noise Cutoff144.70
Domain Noise Cutoff144.70
Isology Typesubfamily
HMM Length1043
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0004527: exonuclease activity molecular_function
GO:0006260: DNA replication biological_process
GO:0006310: DNA recombination biological_process
AuthorLoftus BJ, Eisen JA
Entry DateOct 20 1999 11:56AM
Last ModifiedFeb 14 2011 3:27PM
CommentAll proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
ReferencesA2 hmmalign GA hmmsearch DR EGAD; 7288; DR SWISSPROT; P13458; RM 90045931;