HMM Summary Page: TIGR00617

Functionreplication factor-a protein 1 (rpa1)
Trusted Cutoff334.20
Domain Trusted Cutoff334.20
Noise Cutoff271.45
Domain Noise Cutoff271.45
Isology Typesubfamily
HMM Length608
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
AuthorLoftus BJ, Eisen JA
Entry DateOct 20 1999 11:53AM
Last ModifiedFeb 14 2011 3:27PM
CommentAll proteins in this family for which functions are known are part of a multiprotein complex made up of homologs of RPA1, RPA2 and RPA3 that bind ssDNA and function in the recognition of DNA damage for nucleotide excision repair This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
ReferencesA2 hmmalign GA hmmsearch DR EGAD; 50596; DR SWISSPROT; P22336; RM 91357474;