HMM Summary Page: TIGR00616

Functionrecombinase, phage RecT family
Trusted Cutoff52.65
Domain Trusted Cutoff52.65
Noise Cutoff50.50
Domain Noise Cutoff50.50
Isology Typesubfamily
HMM Length242
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
AuthorLoftus BJ, Eisen JA
Entry DateOct 20 1999 11:53AM
Last ModifiedFeb 14 2011 3:27PM
CommentAll proteins in this family for which functions are known bind ssDNA and are involved in the the pairing of homologous DNA This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). RecT and homologs are found in prophage regions of bacterial genomes. RecT works with a partner protein, RecE.
ReferencesA2 hmmalign DR PFAM; PF03837 DR SWISSPROT; P33228; RN [1] RM 94064562 RT Genetic and molecular analyses of the C-terminal region of the recE gene from the Rac prophage of Escherichia coli K-12 reveal the recT gene. RA Clark AJ, Sharma V, Brenowitz S, Chu CC, Sandler S, Satin L, Templin A, Berger I, Cohen A. RL J Bacteriol. 1993 Dec;175(23):7673-82. RN [2] RM 10921910 RT RecE/RecT and Redalpha/Redbeta initiate double-stranded break repair by specifically interacting with their respective partners. RA Muyrers JP, Zhang Y, Buchholz F, Stewart AF. RL Genes Dev. 2000 Aug 1;14(15):1971-82.