HMM Summary Page: TIGR00614

FunctionATP-dependent DNA helicase, RecQ family
Trusted Cutoff219.80
Domain Trusted Cutoff219.80
Noise Cutoff182.00
Domain Noise Cutoff182.00
Isology Typesubfamily
EC Number3.6.4.12
HMM Length470
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0004386: helicase activity molecular_function
GO:0006310: DNA recombination biological_process
AuthorLoftus BJ, Eisen JA
Entry DateOct 20 1999 11:53AM
Last ModifiedFeb 14 2011 3:27PM
CommentAll proteins in this family for which functions are known are 3'-5' DNA-DNA helicases. These proteins are used for recombination, recombinational repair, and possibly maintenance of chromosome stability. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
ReferencesA2 hmmalign GA hmmsearch DR SWISSPROT; P15043; RM 87115164;