HMM Summary Page: TIGR00596

FunctionDNA repair protein (rad1)
Trusted Cutoff806.65
Domain Trusted Cutoff806.65
Noise Cutoff346.10
Domain Noise Cutoff346.10
Isology Typesubfamily
HMM Length813
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
AuthorLoftus BJ, Eisen JA
Entry DateOct 19 1999 6:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentAll proteins in this family for which functions are known are components in a multiprotein endonuclease complex (usually made up of Rad1 and Rad10 homologs). This complex is used primarily for nucleotide excision repair but also for some aspects of recombinational repair in some species. Most Archaeal species also have homologs of these genes, but the function of these Archaeal genes is not known, so we have set our cutoff to only pick up the eukaryotic genes. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford Universit
ReferencesA2 hmmalign GA hmmsearch GA hmmsearch DR EGAD; 56235; DR SWISSPROT; P06777; RM 87172766;