| Accession | TIGR00580 |
| Name | mfd |
| Function | transcription-repair coupling factor |
| Gene Symbol | mfd |
| Trusted Cutoff | 819.85 |
| Domain Trusted Cutoff | 819.85 |
| Noise Cutoff | 533.00 |
| Domain Noise Cutoff | 533.00 |
| Isology Type | equivalog |
| EC Number | 3.6.1.- |
| HMM Length | 923 |
| Mainrole Category | DNA metabolism |
| Subrole Category | DNA replication, recombination, and repair |
| Gene Ontology Term | GO:0003690: double-stranded DNA binding molecular_function |
| | GO:0005515: protein binding molecular_function |
| | GO:0005524: ATP binding molecular_function |
| | GO:0006281: DNA repair biological_process |
| | GO:0016887: ATPase activity molecular_function |
| Author | Loftus BJ, Eisen JA |
| Entry Date | Oct 19 1999 6:19PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | All proteins in this family for which functions are known are DNA-dependent ATPases that function in the process of transcription-coupled DNA repair in which the repair of the transcribed strand of actively transcribed genes is repaired at a higher rate than the repair of non-transcribed regions of the genome and than the non-transcribed strand of the same gene. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). This family is closely related to the RecG and UvrB families. |
| References | DR SWISSPROT; P30958;
RM 93219833; |
| Genome Property | GenProp0229: transcription-coupled nucleotide excision repair (HMM) |
