HMM Summary Page: TIGR00578

FunctionATP-dependent DNA helicase II, 70 kDa subunit (ku70)
Trusted Cutoff194.25
Domain Trusted Cutoff194.25
Noise Cutoff154.65
Domain Noise Cutoff154.65
Isology Typesuperfamily
HMM Length586
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
AuthorLoftus BJ, Eisen JA
Entry DateOct 19 1999 6:19PM
Last ModifiedFeb 28 2011 3:55PM
CommentProteins in this family are involved in non-homologous end joining, a process used for the repair of double stranded DNA breaks. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). Cutoff does not detect the putative ku70 homologs in yeast.
ReferencesA2 hmmalign GA hmmsearch DR SWISSPROT; P12956; RM 89174787;