HMM Summary Page: TIGR00577

FunctionDNA-formamidopyrimidine glycosylase
Gene SymbolmutM
Trusted Cutoff203.30
Domain Trusted Cutoff203.30
Noise Cutoff105.10
Domain Noise Cutoff105.10
Isology Typeequivalog
EC Number3.2.2.23
HMM Length276
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0005737: cytoplasm cellular_component
GO:0006281: DNA repair biological_process
GO:0008534: oxidized purine base lesion DNA N-glycosylase activity molecular_function
AuthorLoftus BJ, Eisen JA
Entry DateOct 19 1999 6:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentAll proteins in the FPG family with known functions are FAPY-DNA glycosylases that function in base excision repair. Homologous to endonuclease VIII (nei). This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
ReferencesGA hmmsearch GA hmmsearch GA hmmsearch DR EGAD; 8852; DR SWISSPROT; P05523; RM 88082692; DR HAMAP; MF_00103; 329 of 333
Genome PropertyGenProp1099: 8-oxoguanine DNA repair (HMM)