HMM Summary Page: TIGR00574

FunctionDNA ligase I, ATP-dependent (dnl1)
Trusted Cutoff217.80
Domain Trusted Cutoff217.80
Noise Cutoff171.15
Domain Noise Cutoff171.15
Isology Typesuperfamily
EC Number6.5.1.1
HMM Length527
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
AuthorLoftus BJ, Eisen JA
Entry DateOct 19 1999 6:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentAll proteins in this family with known functions are ATP-dependent DNA ligases. Functions include DNA repair, DNA replication, and DNA recombination (or any process requiring ligation of two single-stranded DNA sections). This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
ReferencesGA hmmsearch GA hmmsearch DR EGAD; 51433; DR SWISSPROT; P04819; RM 86093646; DR HAMAP; MF_00407; 39 of 39