| Accession | TIGR00567 |
| Name | 3mg |
| Function | DNA-3-methyladenine glycosylase |
| Trusted Cutoff | 116.35 |
| Domain Trusted Cutoff | 116.35 |
| Noise Cutoff | 75.80 |
| Domain Noise Cutoff | 75.80 |
| Isology Type | subfamily |
| EC Number | 3.2.2.- |
| HMM Length | 192 |
| Mainrole Category | DNA metabolism |
| Subrole Category | DNA replication, recombination, and repair |
| Gene Ontology Term | GO:0006281: DNA repair biological_process |
| | GO:0019104: DNA N-glycosylase activity molecular_function |
| Author | Loftus BJ, Eisen JA |
| Entry Date | Oct 19 1999 6:19PM |
| Last Modified | Sep 16 2014 3:59PM |
| Comment | This families are based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). All proteins in this family for which the function is known are involved in the base excision repair of alkylation damage to DNA. The exact specificty of the type of alkylation damage repaired by each of these varies somewhat between species. Substrates include 3-methyl adenine, 7-methyl-guanaine, and 3-methyl-guanine. |
| References | DR SWISSPROT; P94378;
RM MEDLINE: 97124196;
DR HAMAP; MF_00527; 159 of 162 |
