| Accession | TIGR00565 |
| Name | trpE_proteo |
| Function | anthranilate synthase component I |
| Gene Symbol | trpE |
| Trusted Cutoff | 494.65 |
| Domain Trusted Cutoff | 494.65 |
| Noise Cutoff | 341.10 |
| Domain Noise Cutoff | 341.10 |
| Isology Type | equivalog |
| EC Number | 4.1.3.27 |
| HMM Length | 498 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Aromatic amino acid family |
| Gene Ontology Term | GO:0000162: tryptophan biosynthetic process biological_process |
| | GO:0004049: anthranilate synthase activity molecular_function |
| Author | Haft DH |
| Entry Date | Oct 19 1999 4:31PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This enzyme resembles some other chorismate-binding enzymes, including para-aminobenzoate synthase (pabB) and isochorismate synthase. There is a fairly deep split between two sets, seen in the pattern of gaps as well as in amino acid sequence differences. This group includes proteobacteria such as E. coli and Helicobacter pylori but also the gram-positive organism Corynebacterium glutamicum. The second group includes eukaryotes, archaea, and most other bacterial lineages; sequences from the second group may resemble pabB more closely than other trpE from this group.
|
| References | A2 hmmalign
DR PFAM; PF00425; chorismate_bind
|
| Genome Property | GenProp0037: tryptophan biosynthesis from ribose-5-phosphate (HMM) |
