HMM Summary Page: TIGR00560

FunctionCDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
Gene SymbolpgsA
Trusted Cutoff109.10
Domain Trusted Cutoff109.10
Noise Cutoff72.30
Domain Noise Cutoff72.30
Isology Typeequivalog
EC Number2.7.8.5
HMM Length183
Mainrole CategoryFatty acid and phospholipid metabolism
Subrole CategoryBiosynthesis
Gene Ontology TermGO:0008444: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity molecular_function
GO:0008654: phospholipid biosynthetic process biological_process
AuthorHaft DH
Entry DateOct 19 1999 4:30PM
Last ModifiedFeb 14 2011 3:27PM
CommentAlternate names: phosphatidylglycerophosphate synthase; glycerophosphate phosphatidyltransferase; PGP synthase. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. There may be problems with incorrect transitive annotation of near homologs as authentic CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.
ReferencesAL Clustalw; DR EG10706; pgsA; DR PROSITE; PDOC00321; CDP-alcohol phosphatidyltransferases signature DR PFAM; CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase DR HAMAP; MF_01437; 27 of 27