HMM Summary Page: TIGR00558

Functionpyridoxamine 5'-phosphate oxidase
Gene SymbolpdxH
Trusted Cutoff150.10
Domain Trusted Cutoff150.10
Noise Cutoff128.85
Domain Noise Cutoff128.85
Isology Typeequivalog
EC Number1.4.3.5
HMM Length217
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryPyridoxine
Gene Ontology TermGO:0004733: pyridoxamine-phosphate oxidase activity molecular_function
GO:0008615: pyridoxine biosynthetic process biological_process
AuthorHaft DH
Entry DateOct 19 1999 4:30PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM is similar to Pyridox_oxidase from PFAM but is designed to find only true pyridoxamine-phosphate oxidase and to ignore the related protein PhzG involved in phenazine biosynthesis. This protein from E. coli was characterized as a homodimer with two FMN per dimer.
ReferencesDR PFAM; PF01243; Pyridox_oxidase DR PROSITE; PDOC00815; Pyridoxamine 5'-phosphate oxidase signature DR SWISS-PROT; P28225; PDXH_ECOLI; AL clustalw_manual RM 98359888 RT Expression, purification, and characterization of recombinant Escherichia coli pyridoxine 5'-phosphate oxidase. RA Di Salvo M, Yang E, Zhao G, Winkler ME, Schirch V RL Protein Expr Purif 1998 Aug;13(3):349-56 DR HAMAP; MF_01629; 255 of 271