HMM Summary Page: TIGR00557

Function4-hydroxythreonine-4-phosphate dehydrogenase PdxA
Gene SymbolpdxA
Trusted Cutoff290.35
Domain Trusted Cutoff290.35
Noise Cutoff252.75
Domain Noise Cutoff252.75
Isology Typeequivalog
EC Number1.1.1.262
HMM Length320
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryPyridoxine
Gene Ontology TermGO:0008615: pyridoxine biosynthetic process biological_process
GO:0050570: 4-hydroxythreonine-4-phosphate dehydrogenase activity molecular_function
AuthorHaft DH
Entry DateOct 19 1999 4:30PM
Last ModifiedMay 16 2012 6:50PM
CommentThis HMM represents PdxA, an NAD+-dependent 4-hydroxythreonine 4-phosphate dehydrogenase (EC active in pyridoxal phosphate biosynthesis.
ReferencesRM 99239931 RT Vitamin B6 biosynthesis: formation of pyridoxine 5'-phosphate from 4-(phosphohydroxy)-L-threonine and 1-deoxy-D-xylulose-5-phosphate by PdxA and PdxJ protein. RA Laber B, Maurer W, Scharf S, Stepusin K, Schmidt FS RL FEBS Lett 1999 Apr 16;449(1):45-8 DR HAMAP; MF_00536; 96 of 101
Genome PropertyGenProp0862: pyridoxal phosphate biosynthesis, PdxA/PdxJ pathway (HMM)