HMM Summary Page: TIGR00556

Functionphosphopantetheine--protein transferase domain
Trusted Cutoff45.35
Domain Trusted Cutoff45.35
Noise Cutoff32.00
Domain Noise Cutoff32.00
Isology Typedomain
HMM Length128
Mainrole CategoryProtein fate
Subrole CategoryProtein modification and repair
AuthorHaft DH
Entry DateOct 19 1999 4:30PM
Last ModifiedMar 16 2011 7:46PM
CommentThis HMM models a domain active in transferring the phophopantetheine prosthetic group to its attachment site on enzymes and carrier proteins. Many members of this family are small proteins that act on the acyl carrier protein involved in fatty acid biosynthesis. Some members are domains of larger proteins involved specialized pathways for the synthesis of unusual molecules including polyketides, atypical fatty acids, and antibiotics.
ReferencesDR HAMAP; MF_00101; 389 of 394