| Accession | TIGR00554 |
| Name | panK_bact |
| Function | pantothenate kinase |
| Gene Symbol | coaA |
| Trusted Cutoff | 306.20 |
| Domain Trusted Cutoff | 306.20 |
| Noise Cutoff | 185.70 |
| Domain Noise Cutoff | 185.70 |
| Isology Type | equivalog |
| EC Number | 2.7.1.33 |
| HMM Length | 307 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Pantothenate and coenzyme A |
| Gene Ontology Term | GO:0004594: pantothenate kinase activity molecular_function |
| | GO:0015937: coenzyme A biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Oct 19 1999 4:30PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Shown to be a homodimer in E. coli. This enzyme catalyzes the rate-limiting step in the biosynthesis of coenzyme A. It is very well conserved from E. coli to B. subtilis, but differs considerably from known eukaryotic forms, described in a separate model. |
| References | RM 95014575
RT Kinetics and regulation of pantothenate kinase from Escherichia coli.
RA Song WJ, Jackowski S
RL J Biol Chem 1994 Oct 28;269(43):27051-8
DR HAMAP; MF_00215; 158 of 161 |
| Genome Property | GenProp0171: coenzyme A biosynthesis from pantothenate (HMM) |
