HMM Summary Page: TIGR00540

Functionheme biosynthesis-associated TPR protein
Gene SymbolhemY
Trusted Cutoff142.00
Domain Trusted Cutoff142.00
Noise Cutoff138.00
Domain Noise Cutoff138.00
Isology Typehypoth_equivalog
HMM Length385
Mainrole CategoryUnknown function
Subrole CategoryGeneral
AuthorHaft DH
Entry DateOct 19 1999 4:29PM
Last ModifiedDec 9 2011 1:01PM
CommentMembers of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis.