HMM Summary Page: TIGR00530

Function1-acylglycerol-3-phosphate O-acyltransferases
Trusted Cutoff102.95
Domain Trusted Cutoff102.95
Noise Cutoff44.30
Domain Noise Cutoff44.30
Isology Typesubfamily_domain
EC Number2.3.1.51
HMM Length130
Mainrole CategoryFatty acid and phospholipid metabolism
Subrole CategoryBiosynthesis
AuthorHaft DH
Entry DateOct 19 1999 4:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase.
ReferencesA2 hmmalign DR EC AL ClustalW_manual