HMM Summary Page: TIGR00528

Functionglycine cleavage system T protein
Gene SymbolgcvT
Trusted Cutoff235.85
Domain Trusted Cutoff235.85
Noise Cutoff176.05
Domain Noise Cutoff176.05
Isology Typeequivalog
EC Number2.1.2.10
HMM Length362
Mainrole CategoryEnergy metabolism
Subrole CategoryAmino acids and amines
Gene Ontology TermGO:0004047: aminomethyltransferase activity molecular_function
GO:0005737: cytoplasm cellular_component
GO:0019464: glycine decarboxylation via glycine cleavage system biological_process
AuthorHaft DH
Entry DateOct 18 1999 5:03PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe glycine cleavage system T protein (GcvT) is also known as aminomethyltransferase (EC It works with the H protein (GcvH), the P protein (GcvP), and lipoamide dehydrogenase. The reported sequence of the member from Aquifex aeolicus starts about 50 residues downstream of the start of other members of the family (perhaps in error); it scores below the trusted cutoff. Eukaryotic forms are mitochondrial and have an N-terminal transit peptide.
ReferencesAL clustalw DR HAMAP; MF_00259; 214 of 217
Genome PropertyGenProp0178: glycine cleavage system (HMM)