| Accession | TIGR00516 |
| Name | acpS |
| Function | holo-[acyl-carrier-protein] synthase |
| Gene Symbol | acpS |
| Trusted Cutoff | 59.80 |
| Domain Trusted Cutoff | 59.80 |
| Noise Cutoff | 35.25 |
| Domain Noise Cutoff | 35.25 |
| Isology Type | equivalog_domain |
| EC Number | 2.7.8.7 |
| HMM Length | 125 |
| Mainrole Category | Fatty acid and phospholipid metabolism |
| Subrole Category | Biosynthesis |
| Gene Ontology Term | GO:0008610: lipid biosynthetic process biological_process |
| | GO:0008897: holo-[acyl-carrier-protein] synthase activity molecular_function |
| Author | Haft DH |
| Entry Date | Oct 18 1999 5:03PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Formerly dpj. This enzyme adds the prosthetic group, phosphopantethiene, to the acyl carrier protein (ACP) apo-enzyme to generate the holo-enzyme. Related phosphopantethiene--protein transferases also exist. There is an orthologous domain in eukaryotic proteins. |
| References | RM 96027548
RT Cloning, overproduction, and characterization of the Escherichia coli holo-acyl carrier protein synthase.
RA Lambalot RH, Walsh CT
RL J Biol Chem 1995 Oct 20;270(42):24658-61
DR HAMAP; MF_00101; 359 of 394 |
| Genome Property | GenProp1104: acyl carrier protein phosphopantetheinylation (HMM) |
