HMM Summary Page: TIGR00513

Functionacetyl-CoA carboxylase, carboxyl transferase, alpha subunit
Gene SymbolaccA
Trusted Cutoff319.30
Domain Trusted Cutoff319.30
Noise Cutoff171.15
Domain Noise Cutoff171.15
Isology Typeequivalog
EC Number6.4.1.2
HMM Length321
Mainrole CategoryFatty acid and phospholipid metabolism
Subrole CategoryBiosynthesis
Gene Ontology TermGO:0003989: acetyl-CoA carboxylase activity molecular_function
GO:0006633: fatty acid biosynthetic process biological_process
GO:0009317: acetyl-CoA carboxylase complex cellular_component
AuthorHaft DH
Entry DateOct 18 1999 5:03PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe enzyme acetyl-CoA carboxylase contains a biotin carboxyl carrier protein or domain, a biotin carboxylase, and a carboxyl transferase. This model represents the alpha chain of the carboxyl transferase for cases in which the architecture of the protein is as in E. coli, in which the carboxyltransferase portion consists of two non-identical subnits, alpha and beta.
ReferencesRM 92380982 RT The genes encoding the two carboxyltransferase subunits of Escherichia coli acetyl-CoA carboxylase. RA Li SJ, Cronan JE Jr RL J Biol Chem 1992 Aug 25;267(24):16841-7 DR HAMAP; MF_00823; 312 of 316
Genome PropertyGenProp0214: acetyl-CoA carboxylase complex (HMM)