HMM Summary Page: TIGR00497

Functiontype I restriction-modification system, M subunit
Gene SymbolhsdM
Trusted Cutoff242.75
Domain Trusted Cutoff242.75
Noise Cutoff139.20
Domain Noise Cutoff139.20
Isology Typeequivalog
EC Number2.1.1.72
HMM Length515
Mainrole CategoryDNA metabolism
Subrole CategoryRestriction/modification
Gene Ontology TermGO:0006306: DNA methylation biological_process
GO:0009007: site-specific DNA-methyltransferase (adenine-specific) activity molecular_function
GO:0009307: DNA restriction-modification system biological_process
GO:0015666: restriction endodeoxyribonuclease activity molecular_function
AuthorLoftus BJ
Entry DateApr 20 1999 2:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentFunction: methylation of specific adenine residues; required for both restriction and modification activities. The ECOR124/3 I enzyme recognizes 5'GAA(N7)RTCG. for E.coli see (J. Mol. Biol. 257: 960-969 (1996)).
ReferencesA2 hmmalign DR Swissprot; P10484; DR PROSITE; PDOC00087 RM Medline; 97415765; SE TIGR GA hmmls AL clustalw, belvu BD 0526