HMM Summary Page: TIGR00493

FunctionATP-dependent Clp endopeptidase, proteolytic subunit ClpP
Gene SymbolclpP
Trusted Cutoff308.60
Domain Trusted Cutoff308.60
Noise Cutoff59.20
Domain Noise Cutoff59.20
Isology Typeequivalog
EC Number3.4.21.92
HMM Length192
Mainrole CategoryProtein fate
Subrole CategoryDegradation of proteins, peptides, and glycopeptides
Gene Ontology TermGO:0004176: ATP-dependent peptidase activity molecular_function
GO:0004252: serine-type endopeptidase activity molecular_function
GO:0006508: proteolysis biological_process
GO:0009368: endopeptidase Clp complex cellular_component
AuthorAnolik RT, Haft DH
Entry DateApr 20 1999 2:06PM
Last ModifiedFeb 2 2012 11:16AM
CommentThis model for the proteolytic subunit ClpP has been rebuilt to a higher stringency. In every bacterial genome with the ClpXP machine, a ClpP protein will be found that scores at least 370 by this HMM. In general, this ClpP member will be encoded adjacent to the clpX gene, as were all examples used in the seed alignment. A large fraction of genomes have one or more additional ClpP paralogs, sometimes encoded nearby and sometimes elsewhere. The stringency of the trusted cutoff used here excludes the more divergent ClpP paralogs from being called authentic ClpP by this model.
ReferencesDR PROSITE; PDOC00358; SE TIGR GA hmmls DR HAMAP; MF_00444; 354 of 624
Genome PropertyGenProp0251: clpXP degradation machine (HMM)