HMM Summary Page: TIGR00488

Functionputative HD superfamily hydrolase
Trusted Cutoff70.15
Domain Trusted Cutoff70.15
Noise Cutoff62.00
Domain Noise Cutoff62.00
Isology Typehypoth_equivalog
HMM Length173
Mainrole CategoryUnknown function
Subrole CategoryEnzymes of unknown specificity
AuthorAnolik RT, Richardson DL, Haft DH
Entry DateApr 20 1999 2:06PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe function of this protein family is unknown. Members of this family of uncharacterized proteins from the Mycoplasmas are longer at the amino end, fused to a region of nicotinamide nucleotide adenylyltransferase, an NAD salvage biosynthesis enzyme. Members are putative metal-dependent phosphohydrolases for NAD metabolism.
ReferencesDR PDB; 2O08; Crystal Structure Of A Putative Hd Superfamily Hydrolase (Np_242193.1) From Bacillus Halodurans DR PDB; 3CCG; Crystal Structure Of Predicted Hd Superfamily Hydrolase Involved In Nad Metabolism (Np_347894.1) From Clostridium Acetobutylicum At 1.50 A Resolution DR PDB; 2OGI; Crystal Structure Of A Putative Metal Dependent Phosphohydrolase (Np_688652.1) From Streptococcus Agalactiae 2603 At 1.85 A Resolution