| Accession | TIGR00487 |
| Name | IF-2 |
| Function | translation initiation factor IF-2 |
| Gene Symbol | infB |
| Trusted Cutoff | 424.40 |
| Domain Trusted Cutoff | 424.40 |
| Noise Cutoff | 354.60 |
| Domain Noise Cutoff | 354.60 |
| Isology Type | equivalog |
| HMM Length | 587 |
| Mainrole Category | Protein synthesis |
| Subrole Category | Translation factors |
| Gene Ontology Term | GO:0003743: translation initiation factor activity molecular_function |
| | GO:0005737: cytoplasm cellular_component |
| | GO:0006413: translational initiation biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:04PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model discriminates eubacterial (and mitochondrial) translation initiation factor 2 (IF-2), encoded by the infB gene in bacteria, from similar proteins in the Archaea and Eukaryotes. In the bacteria and in organelles, the initiator tRNA is charged with N-formyl-Met instead of Met. This translation factor acts in delivering the initator tRNA to the ribosome. It is one of a number of GTP-binding translation factors recognized by the pfam HMM GTP_EFTU. |
| References | SE TIGR
GA hmmls
AL clustalw
DR HAMAP; MF_00100; 552 of 608 |
| Genome Property | GenProp0740: translation initiation, bacterial (HMM) |
| | GenProp0799: bacterial core gene set, exactly 1 per genome (HMM) |
