HMM Summary Page: TIGR00487

Functiontranslation initiation factor IF-2
Gene SymbolinfB
Trusted Cutoff424.40
Domain Trusted Cutoff424.40
Noise Cutoff354.60
Domain Noise Cutoff354.60
Isology Typeequivalog
HMM Length587
Mainrole CategoryProtein synthesis
Subrole CategoryTranslation factors
Gene Ontology TermGO:0003743: translation initiation factor activity molecular_function
GO:0005737: cytoplasm cellular_component
GO:0006413: translational initiation biological_process
AuthorHaft DH
Entry DateApr 20 1999 2:04PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model discriminates eubacterial (and mitochondrial) translation initiation factor 2 (IF-2), encoded by the infB gene in bacteria, from similar proteins in the Archaea and Eukaryotes. In the bacteria and in organelles, the initiator tRNA is charged with N-formyl-Met instead of Met. This translation factor acts in delivering the initator tRNA to the ribosome. It is one of a number of GTP-binding translation factors recognized by the pfam HMM GTP_EFTU.
ReferencesSE TIGR GA hmmls AL clustalw DR HAMAP; MF_00100; 552 of 608
Genome PropertyGenProp0740: translation initiation, bacterial (HMM)
GenProp0799: bacterial core gene set, exactly 1 per genome (HMM)