HMM Summary Page: TIGR00486

Functiondinuclear metal center protein, YbgI/SA1388 family
Trusted Cutoff130.55
Domain Trusted Cutoff130.55
Noise Cutoff107.15
Domain Noise Cutoff107.15
Isology Typehypoth_equivalog
HMM Length250
Mainrole CategoryUnknown function
Subrole CategoryGeneral
Gene Ontology TermGO:0005737: cytoplasm cellular_component
GO:0008150: biological_process biological_process
GO:0051540: metal cluster binding molecular_function
AuthorAnolik RT, Richardson DL, Haft DH
Entry DateApr 20 1999 2:06PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe characterization of this family of uncharacterized proteins as orthologous is tentative. Members are found in all three domains of life. Several members (from Bacillus subtilis, Listeria monocytogenes, and Mycobacterium tuberculosis - all classified as Firmicutes within the Eubacteria) share a long insert relative to other members.
ReferencesRN [1] RM PMID:14519207 RT Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site. RA Ladner JE, Obmolova G, Teplyakov A, Howard AJ, Khil PP, Camerini-Otero RD, Gilliland GL RL BMC Struct Biol. 2003 Sep 30;3:7. RN [2] RM PMID:17187687 RT Structure of a conserved hypothetical protein SA1388 from S. aureus reveals a capped hexameric toroid with two PII domain lids and a dinuclear metal center. RA Saikatendu KS, Zhang X, Kinch L, Leybourne M, Grishin NV, Zhang H RL BMC Struct Biol. 2006 Dec 23;6:27.