| Accession | TIGR00484 |
| Name | EF-G |
| Function | translation elongation factor G |
| Gene Symbol | fusA |
| Trusted Cutoff | 659.40 |
| Domain Trusted Cutoff | 659.40 |
| Noise Cutoff | 215.15 |
| Domain Noise Cutoff | 215.15 |
| Isology Type | equivalog |
| HMM Length | 691 |
| Mainrole Category | Protein synthesis |
| Subrole Category | Translation factors |
| Gene Ontology Term | GO:0003746: translation elongation factor activity molecular_function |
| | GO:0006414: translational elongation biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:03PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | After peptide bond formation, this elongation factor of bacteria and organelles catalyzes the translocation of the tRNA-mRNA complex, with its attached nascent polypeptide chain, from the A-site to the P-site of the ribosome. Every completed bacterial genome has at least one copy, but some species have additional EF-G-like proteins. The closest homolog to canonical (e.g. E. coli) EF-G in the spirochetes clusters as if it is derived from mitochondrial forms, while a more distant second copy is also present. Synechocystis PCC6803 has a few proteins more closely related to EF-G than to any other characterized protein. Two of these resemble E. coli EF-G more closely than does the best match from the spirochetes; it may be that both function as authentic EF-G. |
| References | SE TIGR
GA hmmls
AL clustalw
DR HAMAP; MF_00054; 559 of 618 |
| Genome Property | GenProp0741: translation elongation, bacterial (HMM) |
| | GenProp0800: bacterial core gene set, 1 or more per genome (HMM) |
