| Accession | TIGR00463 |
| Name | gltX_arch |
| Function | glutamate--tRNA ligase |
| Gene Symbol | gltX |
| Trusted Cutoff | 401.75 |
| Domain Trusted Cutoff | 401.75 |
| Noise Cutoff | 384.75 |
| Domain Noise Cutoff | 384.75 |
| Isology Type | equivalog |
| EC Number | 6.1.1.17 |
| HMM Length | 560 |
| Mainrole Category | Protein synthesis |
| Subrole Category | tRNA aminoacylation |
| Gene Ontology Term | GO:0004818: glutamate-tRNA ligase activity molecular_function |
| | GO:0006424: glutamyl-tRNA aminoacylation biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:07PM |
| Last Modified | Oct 11 2011 12:16PM |
| Comment | The glutamyl-tRNA synthetases of the eukaryotic cytosol and of the Archaea are more similar to glutaminyl-tRNA synthetases than to bacterial glutamyl-tRNA synthetases. This HMM models just the eukaryotic cytosolic and archaeal forms of the enzyme. In some eukaryotes, the glutamyl-tRNA synthetase is part of a longer, multifunctional aminoacyl-tRNA ligase. In many species, the charging of tRNA(gln) proceeds first through misacylation with Glu and then transamidation. For this reason, glutamyl-tRNA synthetases, including all known archaeal enzymes (as of 2010) may act on both tRNA(gln) and tRNA(glu). |
| References | SE TIGR
GA hmmls
DR HAMAP; MF_00022; 42 of 565 |
| Genome Property | GenProp0217: 5-aminolevulinate biosynthesis (glutamate pathway) (HMM) |
| | GenProp0258: tRNA aminoacylation (HMM) |
| | GenProp0831: archaeal core gene set, exactly 1 per genome (HMM) |
