| Accession | TIGR00460 |
| Name | fmt |
| Function | methionyl-tRNA formyltransferase |
| Gene Symbol | fmt |
| Trusted Cutoff | 201.50 |
| Domain Trusted Cutoff | 201.50 |
| Noise Cutoff | 178.75 |
| Domain Noise Cutoff | 178.75 |
| Isology Type | equivalog |
| EC Number | 2.1.2.9 |
| HMM Length | 315 |
| Mainrole Category | Protein synthesis |
| Subrole Category | tRNA aminoacylation |
| Gene Ontology Term | GO:0004479: methionyl-tRNA formyltransferase activity molecular_function |
| | GO:0005737: cytoplasm cellular_component |
| | GO:0006431: methionyl-tRNA aminoacylation biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:07PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The top-scoring characterized proteins other than methionyl-tRNA formyltransferase (fmt) itself are formyltetrahydrofolate dehydrogenases. The mitochondrial methionyl-tRNA formyltransferases are so divergent that, in a multiple alignment of bacterial fmt, mitochondrial fmt, and formyltetrahydrofolate dehydrogenases, the mitochondrial fmt appears the most different. However, because both bacterial and mitochondrial fmt are included in the seed alignment, all credible fmt sequences score higher than any non-fmt sequence. This enzyme modifies Met on initiator tRNA to f-Met. |
| References | SE TIGR
GA hmmls
AL clustalw_manual
DR HAMAP; MF_00182; 452 of 467 |
| Genome Property | GenProp0799: bacterial core gene set, exactly 1 per genome (HMM) |
