| Accession | TIGR00453 |
| Name | ispD |
| Function | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase |
| Gene Symbol | ispD |
| Trusted Cutoff | 181.30 |
| Domain Trusted Cutoff | 181.30 |
| Noise Cutoff | 87.20 |
| Domain Noise Cutoff | 87.20 |
| Isology Type | equivalog_domain |
| EC Number | 2.7.7.60 |
| HMM Length | 219 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Other |
| Gene Ontology Term | GO:0019288: isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway biological_process |
| | GO:0050518: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity molecular_function |
| Author | Haft DH, Loftus BJ, Nelson WE |
| Entry Date | Apr 20 1999 2:06PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, the IspD protein of the deoxyxylulose pathway of IPP biosynthesis. In about twenty percent of bacterial genomes, this protein occurs as IspDF, a bifunctional fusion protein. |
| References | DR Swissprot; Q06755;
DR Blocks; UPF0007;
DR EXCEPTION; EGAD|18524; CDP-ribitol pyrophosphorylase; Haemophilus influenzae
DR OUTGROUP; OMNI|MT1046; UDP-N-acetylglucosamine pyrophosphorylase; Mycobacterium tuberculosis
DR OUTGROUP; OMNI|CC2304; UDP-N-acetylglucosamine pyrophosphorylase; Caulobacter crescentus
DR EXPERIMENTAL; SP:ISPD_ECOLI; Escherichia coli
DR HAMAP; MF_01520; 70 of 79 |
| Genome Property | GenProp0048: IPP biosynthesis via deoxyxylulose (HMM) |
