| Accession | TIGR00450 |
| Name | mnmE_trmE_thdF |
| Function | tRNA modification GTPase TrmE |
| Gene Symbol | trmE |
| Trusted Cutoff | 252.60 |
| Domain Trusted Cutoff | 252.60 |
| Noise Cutoff | 200.70 |
| Domain Noise Cutoff | 200.70 |
| Isology Type | equivalog |
| EC Number | 3.6.-.- |
| HMM Length | 446 |
| Mainrole Category | Protein synthesis |
| Subrole Category | tRNA and rRNA base modification |
| Gene Ontology Term | GO:0003924: GTPase activity molecular_function |
| | GO:0006400: tRNA modification biological_process |
| Author | Loftus BJ, Haft DH |
| Entry Date | Apr 20 1999 2:10PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | TrmE, also called MnmE and previously designated ThdF (thiophene and furan oxidation protein), is a GTPase involved in tRNA modification to create 5-methylaminomethyl-2-thiouridine in the wobble position of some tRNAs. This protein and GidA form an alpha2/beta2 heterotetramer. |
| References | DR EXPERIMENTAL; OMNI|NTL01EC03627; Escherichia coli
DR ECOCYC; EG10997;
RM 10601028
RT The Escherichia coli trmE (mnmE) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties.
RA Cabedo H, Macian F, Villarroya M, Escudero JC, Martinez-Vicente M, Knecht E, Armengod ME
RL EMBO J 1999 Dec 15;18(24):7063-76
SE TIGR
GA hmmls
DR HAMAP; MF_00379; 519 of 542 |
| Genome Property | GenProp0704: tRNA U34 carboxymethylaminomethyl modification (HMM) |
