| Accession | TIGR00443 |
| Name | hisZ_biosyn_reg |
| Function | ATP phosphoribosyltransferase, regulatory subunit |
| Gene Symbol | hisZ |
| Trusted Cutoff | 271.65 |
| Domain Trusted Cutoff | 271.65 |
| Noise Cutoff | 251.60 |
| Domain Noise Cutoff | 251.60 |
| Isology Type | equivalog |
| HMM Length | 314 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Histidine family |
| Gene Ontology Term | GO:0000105: histidine biosynthetic process biological_process |
| | GO:0003879: ATP phosphoribosyltransferase activity molecular_function |
| | GO:0030234: enzyme regulator activity molecular_function |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:08PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Apparant second copies of histidyl-tRNA synthetase, found in Bacillus subtilis, Synechocystis sp., Aquifex aeolicus, and others, are in fact a regulatory subunit of ATP phosphoribosyltransferase, and usually encoded by a gene adjacent to that encoding the catalytic subunit. |
| References | RN [1]
RM PMID:15660995
RT Regulation of the hetero-octameric ATP phosphoribosyl transferase complex from Thermotoga maritima by a tRNA synthetase-like subunit.
RA Vega MC, Zou P, Fernandez FJ, Murphy GE, Sterner R, Popov A, Wilmanns M
RL Mol Microbiol. 2005 Feb;55(3):675-86.
DR HAMAP; MF_00125; 15 of 170 |
| Genome Property | GenProp0109: histidine biosynthesis from ribose-5-phosphate (HMM) |
