| Accession | TIGR00421 |
| Name | ubiX_pad |
| Function | polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases |
| Trusted Cutoff | 108.90 |
| Domain Trusted Cutoff | 108.90 |
| Noise Cutoff | 69.30 |
| Domain Noise Cutoff | 69.30 |
| Isology Type | subfamily |
| EC Number | 4.1.1.- |
| HMM Length | 181 |
| Mainrole Category | Unknown function |
| Subrole Category | Enzymes of unknown specificity |
| Gene Ontology Term | GO:0006725: cellular aromatic compound metabolic process biological_process |
| | GO:0016831: carboxy-lyase activity molecular_function |
| Author | Loftus BJ, Haft DH |
| Entry Date | Apr 20 1999 2:10PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | In E.coli, the protein UbiX (3-octaprenyl-4-hydroxybenzoate carboxy-lyase) has been shown to be involved in the third step of ubiquinone biosynthesis. It catalyzes the reaction [3-octaprenyl-4-hydroxybenzoate = 2-octaprenylphenol + CO2]. The knockout of the homologous protein in yeast confers sensitivity to phenylacrylic acid. Members are not restricted to ubiquinone-synthesizing species. This family represents a distinct clade within the flavoprotein family of Pfam model PF02441. |
| References | DR Swissprot; P33751;
DR Swissprot; P09550;
SE TIGR
GA hmmls
DR PFAM; PF02441
DR InterPro; IPR003382 |
| Genome Property | GenProp0136: ubiquinone biosynthesis from chorismate, aerobic (HMM) |
