| Accession | TIGR00420 |
| Name | trmU |
| Function | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase |
| Gene Symbol | trmU |
| Trusted Cutoff | 236.95 |
| Domain Trusted Cutoff | 236.95 |
| Noise Cutoff | 185.85 |
| Domain Noise Cutoff | 185.85 |
| Isology Type | equivalog |
| EC Number | 2.1.1.61 |
| HMM Length | 351 |
| Mainrole Category | Protein synthesis |
| Subrole Category | tRNA and rRNA base modification |
| Gene Ontology Term | GO:0004808: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity molecular_function |
| | GO:0005737: cytoplasm cellular_component |
| | GO:0006396: RNA processing biological_process |
| Author | Loftus BJ |
| Entry Date | Apr 20 1999 2:10PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (trmU, asuE, or mnmA) is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine (mnm5s2U34) present in the wobble position of some tRNAs. This enzyme appears not to occur in the Archaea. |
| References | DR Swissprot; P25745
RM 87250459;
DR ECOCYC; EG11344;
SE TIGR
GA hmmls
DR HAMAP; MF_00144; 594 of 628 |
| Genome Property | GenProp0704: tRNA U34 carboxymethylaminomethyl modification (HMM) |
| | GenProp0799: bacterial core gene set, exactly 1 per genome (HMM) |
